When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated
in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest
sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).
Exon names are shown between parentheses on the first line.
The Cysteines involved in the IG CH1, CH2 and CH3 intrachain disulfide bridge are shown with a larger letter C in purple.
The Cysteines involved in the H-L or H-H interchain disulfide bridge are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).
1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
A P T R S P S L F P L T R C C
M15398 ,IGHE*01 (CH1) (G)CC CCC ACA CGG AGC CCA TCC CTC TTC CCC TTG ACC CGC TGC TGC
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
K N I P S N A T S V T L G C L A M G Y
M15398 ,IGHE*01 (CH1) AAA AAC ATT CCC TCC AAT ... GCC ACC TCC GTG ACG CTG GGC TGC CTG GCC ATG GGC TAC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
F P E P V M V T W D A G S L N G
M15398 ,IGHE*01 (CH1) TTC CCG ... ... GAG CCG GTG ATG GTG ACC TGG GAC GCA GGC TCC CTC AAC GGG ... ...
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
T T M T L P A T T L T P S
M15398 ,IGHE*01 (CH1) ... ... ACA ACT ATG ACC TTA CCA GCC ACC ACC CTC ACG CCC TCT ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
G H Y A T I S L L T V S G A W A
M15398 ,IGHE*01 (CH1) GGT CAC TAT GCC ACC ATC AGC TTG CTG ACC GTC TCG GGT GCG TGG ... ... ... ... GCC
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
K Q M F T C R V A H T P S S T D W V D N
M15398 ,IGHE*01 (CH1) AAG CAG ATG TTC ACC TGC CGT GTG GCA CAC ACT CCA TCG TCC ACA GAC TGG GTG GAC AAC
119 120 121 122
K T F S
M15398 ,IGHE*01 (CH1) AAA ACC TTC AGC G
1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
V C S R D F T P T V K V L Q S S C
M15398 ,IGHE*01 (CH2) TC TGC TCC AGG GAC TTC ACG CCC ACC GTG AAG GTC TTA CAG TCG TCC TGT
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
D G G G H F P P T I Q L L C L V S G Y
M15398 ,IGHE*01 (CH2) GAC GGC GGC GGG CAC TTC ... CCC CCG ACC ATC CAG CTC CTG TGC CTC GTC TCT GGG TAC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
T P G T I N I T W L E D G Q V M D
M15398 ,IGHE*01 (CH2) ACC CCA ... ... GGG ACT ATC AAC ATC ACC TGG CTG GAG GAC GGG CAG GTC ATG GAC ...
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
V D L S T A S A T Q E G
M15398 ,IGHE*01 (CH2) ... ... GTG GAC TTG TCC ACC GCC TCT GCC ACG CAG GAG GGT ... ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
E L A S T Q S E L T L S Q K H W L S
M15398 ,IGHE*01 (CH2) GAG CTG GCC TCC ACA CAA AGC GAG CTC ACC CTC AGC CAG AAG CAC TGG ... ... CTG TCG
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
D R T Y T C Q V T Y Q G G T F E
M15398 ,IGHE*01 (CH2) GAC CGC ACC TAC ACC TGC CAG GTC ACC TAT CAA ... ... ... ... GGT GGC ACC TTT GAG
119 120 121 122 123 124 125
D S T K K C A
M15398 ,IGHE*01 (CH2) GAC AGC ACC AAG AAG TGT GCA G
1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
D S N P R G V S A Y L S R P S P
M15398 ,IGHE*01 (CH3) AT TCC AAC CCG AGA GGG GTG AGC GCC TAC CTA AGC CGG CCC AGC CCG
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
F D L F I R K S P T I T C L V V D L
M15398 ,IGHE*01 (CH3) TTC GAC CTG TTC ATC ... ... CGC AAG TCG CCC ACG ATC ACC TGT CTG GTG GTG GAC CTG
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
A P S K G T V N L T W S R A S G K P V
M15398 ,IGHE*01 (CH3) GCA CCC AGC AAG GGG ACC GTG AAC CTG ACC TGG TCC CGG GCC AGT GGG AAG CCT GTG ...
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
N H S T R K Q E K Q R N
M15398 ,IGHE*01 (CH3) ... ... AAC CAC TCC ACC AGA AAG CAG GAG AAG CAG CGC AAC ... ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
G T L T V T S T L P V G T R D W I E
M15398 ,IGHE*01 (CH3) GGC ACG TTA ACC GTC ACG TCC ACC CTG CCG GTG GGC ACC CGA GAC TGG ... ... ATC GAG
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
G E T Y Q C R V T H P H L P R A L V
M15398 ,IGHE*01 (CH3) GGG GAG ACC TAC CAG TGC AGG GTG ACC CAC CCC CAC ... ... CTG CCC AGG GCC CTC GTG
119 120 121 122 123 124 125
R S T T K T S
M15398 ,IGHE*01 (CH3) CGG TCC ACG ACC AAG ACC AGC G
1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11
G P R A A P E V Y A F A T P E
M15398 ,IGHE*01 (CH4) GC CCG CGT GCT GCC CCG GAA GTC TAT GCG TTT GCG ACG CCG GAG
___AB_______ ________
15.1 15.3
12 13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28
G P G S R D K R T L A C L I Q N F
M15398 ,IGHE*01 (CH4) GGG CCG GGG AGC ... ... ... CGG GAC AAG CGC ACC CTC GCC TGC CTG ATC CAG AAC TTC
_________BC_____________________ ___________CD_______
45.1 45.3 45.5
29 30 31 32 33 34 35 36 39 40 41 42 43 44 45 45.2 45.4
M P E D I S V Q W L H N E V Q L P D
M15398 ,IGHE*01 (CH4) ATG CCT ... ... GAG GAC ATC TCG GTG CAG TGG CTG CAC AAC GAG GTG CAG CTC CCG GAC
________ _________________________DE_____________
45.7 84.1 84.3 84.5 84.7 85.6
45.6 77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
A R H S T T Q P H K T K G
M15398 ,IGHE*01 (CH4) GCC ... CGG CAC AGC ACA ACG CAG CCC CAC AAG ACC AAG GGC ... ... ... ... ... ...
________________ _EF_____
85.4 85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98
S G F F V F S R L E V T R A E W E Q
M15398 ,IGHE*01 (CH4) TCC GGC TTC TTC GTC TTC AGC CGC CTG GAG GTG ACC AGG GCC GAA TGG ... ... GAG CAG
_______________________FG___________________________
99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118
K D E F I C R A V H E A A S P S Q T V Q
M15398 ,IGHE*01 (CH4) AAA GAT GAG TTC ATC TGC CGT GCA GTC CAT GAG GCA GCG AGC CCC TCA CAG ACC GTC CAG
CHS____
119 120 121 122 123 124 125 126 127 128 129 130
R T V S V N P G K *
M15398 ,IGHE*01 (CH4) CGA ACG GTG TCT GTA AAT CCC ... ... ... GGT AAA
Created: 12/11/2002
Author: Nathalie Bosc
IMGT Home page |
IMGT Repertoire (IG and TR) |
IMGT Repertoire (MH) |
IMGT Repertoire (RPI) |
IMGT Index |
IMGT Scientific chart |
IMGT Education |
IMGT Latest news 
© Copyright 1995-2024 IMGT®, the international ImMunoGeneTics information system® | Terms of use | About us | Contact us | Citing IMGT